Rigoberto Uran has withdrawn from the Tour de France due to injuries suffered on stage nine.
The EF Education First - Drapac rider crashed on the cobbled 156.5 kilometre ride from Arras to Roubaix on Sunday.
Uran, the runner-up in last year's Tour, had the benefit of a rest day on Monday and has since braved two mountain stages, but finished 26 minutes behind Geraint Thomas on stage 11 on Wednesday.
The Colombian is now 31 minutes off the pace and, with his hopes of contending in the general classification gone, Uran has decided to focus on his recuperation.
"I didn't recover after the crash. Yesterday in the first real climb, all day, there was pain in my body," Uran said.
"It's difficult for me and also for my team. We prepared for this Tour, all season we were focused on the Tour.
“Today I have to share some bad news. I didn’t recover after the crash. Yesterday in the first real climb, all day, there was pain in my body.” - @UranRigoberto #PinkArgyle #TDF2018 leader Rigoberto Uran withdraws due to injuries: https://t.co/gvmAB4H6O7 pic.twitter.com/gDO7cuu5Rf— EF Education First - Drapac p/b Cannondale (@Ride_Argyle) July 19, 2018
"Sometimes this happens, and this time, I think it's the best decision for me to recover and to recover well."
With their team leader out, EF Education First - Drapac will focus on simply winning stages for the remainder of the Tour.
"We'll miss Rigo of course – he's a great leader and a wonderful presence to have on the bus and with the staff," said team CEO Jonathan Vaughters. "We look forward to getting him back healthy for the rest of the season.
"The guys that remain are fighters, and we have some chances coming up in the mountains. For us, another Tour begins."
|Japan see off Uruguay in seven-goal thriller|
|Arda Turan given huge fine by Istanbul Basaksehir after alleged brawl with singer|
|Busquets no better or worse than Dier – does Opta data back up Allardyce claim?|
|United boss Mourinho charged for alleged post-match comments by FA|
|Halep withdraws from Kremlin Cup ahead of WTA Finals|
|Renato Sanches eager for further Bayern Munich minutes|
|Nations League standings: Promotion, relegation and race for finals|
|Windies coach Law banned for ´inappropriate comments´ in India Test|
|Carrick denies Manchester United stars are ´not trying´|
|Ferrari struggling under pressure of chasing Mercedes, says Massa|
|Australia desperately need Smith and Warner back - Warne|
|Draxler warns Germany: Mbappe has 300 hp!|
|Draymond Green says Warriors will have to ´bring it´ every night in the West|
|England´s ´wonderful bravery´ leaves Southgate excited for the future|
|Jayasuriya: I always conduct myself with integrity and transparency|
|Northern Ireland stars hurt by lack of club football, says O´Neill|
|Rodgers inspires late Packers comeback|
|Brewers blank Dodgers to take 2-1 NLCS lead|
|Cavaliers, Nance agree to four-year extension|
|Ramos wants Spain to believe in Luis Enrique´s team|
|De Laurentiis: I´ve spoken to Genoa and agent about Piatek|
|Kaka tips bright future for Paqueta after Milan agreement|
|Suns star Booker set to return for season opener|
|Warriors coach Kerr not expecting fast start from NBA champs|
|Fultz to start for 76ers as Brown eyes NBA Finals|
|Maltese champions Valletta want Usain Bolt|
|It would have been normal to kill them! Luis Enrique slams abysmal Spain|
|Seahawks, Trail Blazers owner Paul Allen dies aged 65|
|Red Sox ace Sale released from hospital, still set for game five|
|Beer-throwing fan banned by Patriots|
|Southgate lauds ´tremendous´ attackers after famous Spain win|
|Djokovic closing in on summit as he scales new heights|
|Monaco the natural move for Henry - Martinez|
|Ending England drought a ´beautiful feeling´ – Sterling|
|Halep to face Pavlyuchenkova in Moscow comeback|
|NBA 2018-19: Five non-LeBron James storylines to follow|
|Spain 2 England 3: Kane inspires Three Lions as Sterling ends drought in style|
|Bosnia-Herzegovina 2 Northern Ireland 0: Dzeko double leaves O´Neill´s side on the brink|
|Mannarino stops the rot in Moscow|
|Neymar pleased Brazil will not face Messi in Argentina clash|
|Buccaneers fire defensive coordinator Mike Smith after loss to Falcons|
|´Surprised´ Deschamps accepts he could´ve made more effort with Koscielny|
|Kuwait 0 Australia 4: Socceroos deliver win for new coach Arnold|
|Van Dijk fit for Liverpool return - Koeman|
|NBA 2018-19: Eastern Conference predictions|
|NBA 2018-19: Five rookies to watch|
|Denly replaces injured Dawson in England ODI squad|
|Low confirms under-fire Neuer to start against France|
|NBA 2018-19: Western Conference predictions|
|Bolt offered two-year deal by European club, says agent|
|NBA 2018-19: LeBron the Laker - what it means|
|Griezmann ahead of Mbappe for Ballon d´Or - Modric|
|Billy Vunipola ruled out with fractured arm|
|Get the chequebook out! - Mayweather talks up potential Khabib clash|
|Amla ruled out of Australia tour|
|Class act Hamilton more complete than ever - Wolff|
|NBA 2018-19: It´s a big season for - Ball, Kawhi, Carmelo, Love & Cousins|
|Bellew: I have no fear of Usyk|
|Birthday boy Ozil is the most creative player in Europe|
|CSA reveals De Villiers and Rabada involved in Mzansi Super League|
|FA condemns England supporters involved in trouble in Seville|
|Gascoigne hits back over Scottish Hall of Fame snub|
|NBA 2018-19: LeBron closing in on Jordan, Curry chasing Miller and Allen|
|Ter Stegen should start ahead of Neuer for Germany – Matthaus|
|England´s Sterling impressed by Sancho´s work ethic|
|Vandoorne seals switch to Formula E|
|Halep to end 2018 as world number one|
|Sri Lanka´s Jayasuriya charged by ICC with breaching anti-corruption code|
|Vermaelen out for six weeks with hamstring injury|
|LeBron and Irving did not fall out, says ex-Cavs trainer|