Real Madrid midfielder Luka Modric could be a doubt for the clash with Paris Saint-Germain on March 6 due to a hamstring injury, Zinedine Zidane has confirmed.
The Croatia international missed training on Tuesday and is set to sit out Wednesday's LaLiga meeting with Leganes at Butarque.
Head coach Zidane hopes the injury is only minor but is uncertain how long Modric will be out of action.
"Modric has a hamstring issue," he told a news conference. "I always have faith in the staff here, the physios and doctors, so he will be back with us quickly. I don't think it is serious."
The injury is the latest to hit the Madrid squad since their 3-1 win over PSG in the first leg of the Champions League last 16 last week.
Toni Kroos has picked up a knee problem and Marcelo limped out of Sunday's 5-3 win over Real Betis with another suspected hamstring issue.
Zidane remains hopeful, though, that all three could return for the meeting at Parc des Princes.
"I am always positive," he said. "I do not like to see today that we have three or four players out injured. I hope they are not out too long, but we will see. I hope it is short.
"It can be that, when there are certain [injury] problems, it's because of an enormous effort. But, at the same time, in order to cope with matches like the one against PSG, we have to repeat those efforts.
"We have to maintain the pressure in every game and to keep doing it for 90 minutes. And doing it every three days is positive.
"When you're winning playing every three days, you're more optimistic. That's what we need now."
|Osaka wows Tokyo crowd on WTA return|
|Excited Povetkin arrives in England for Joshua showdown|
|Kovac patience with Sanches set to reap rewards|
|Kovac: Madrid strong without Ronaldo, Messi is the best|
|ATP suspends umpire Lahyani over Kyrgios ´pep talk´ at US Open|
|North and South Korea seek to co-host 2032 Olympics|
|Ampadu signs long-term Chelsea contract|
|Don´t blame Neymar, PSG players all guilty - Thiago Silva|
|Real Madrid seek to plug Ronaldo scoring gap – Champions League in Opta numbers|
|Brewers allow Cardinals to inch closer with loss to Reds|
|Manchester is still red – Depay ahead of Lyon´s clash with City|
|Orioles become first pro team to wear braille jerseys|
|Klopp hails ´brilliant´ Henderson|
|PSG attack lacked aggression, says Tuchel|
|Atletico Tucuman 0 Gremio 2: Libertadores holders draw first blood in QFs|
|Thomas plays down wrist worry|
|Rakitic wants more from Barcelona hat-trick hero Messi|
|My players aren´t s*** – Pochettino defends Spurs squad|
|Cubs reliever Morrow won´t return this season|
|Tebow expected to be back in Mets organisation next season|
|Inter can compete against anyone – Icardi revels in Champions League victory|
|Tuchel: PSG loss to Liverpool not logical or correct|
|Sturridge in best shape I´ve seen – Klopp|
|Milojevic celebrates ´fantastic´ occasion after Red Star´s 26-year wait|
|Rodrigo and Simeone salute Griezmann display|
|Seahawks DE Clark on Bears QB Trubisky: He´s nothing special|
|Carroll says Wilson has been ´over-trying a little bit´|
|Judge returns to Yankees´ starting lineup|
|Napoli boss Ancelotti takes aim at Red Star time wasting|
|Favre admits young Dortmund stars struggled in Bruges|
|Otavio would trade goal for Porto victory as he bemoans Schalke draw|
|Championship Review: Pacesetters Leeds crush Preston, Villa end five-game winless run|
|Neymar world-class but not a defender - Klopp says Liverpool targeted PSG star|
|Waiters injury update: Heat guard unlikely to be ready for start of season|
|Gojowczyk eliminates returning Tsonga in Metz|
|Liverpool enjoying best start in 57 years after PSG win|
|Galatasaray 3 Lokomotiv Moscow 0: Terim´s side make light work of Russians|
|Club Brugge 0 Borussia Dortmund 1: Super sub Pulisic scores late winner|
|Schalke 1 Porto 1: Fahrmann saves one penalty, but Otavio scores another|
|Red Star Belgrade 0 Napoli 0: Points shared as Italians fail to make possession pay|
|Liverpool 3 Paris Saint-Germain 2: Firmino strikes late as Reds edge five-goal thriller|
|Monaco 1 Atletico Madrid 2: Costa and Gimenez seal comfortable win|
|Chaos reigns in Serie B as league denies suspension claim|
|India secure Asia Cup victory despite valiant Hong Kong effort|
|Messi makes "extraordinary routine", says Valverde after Barca star surpasses Ronaldo|
|Spalletti´s Inter to take heart from Tottenham turnaround|
|Casillas features in landmark 20th Champions League campaign|
|Spurs deserved more from best performance of the season - Pochettino|
|Brown absent from Steelers facility on Monday due to ´personal matter´|
|Toronto´s Bussey given eight-match biting ban|
|Barcelona 4 PSV 0: Marvellous Messi lights up Camp Nou|
|Inter 2 Tottenham 1: Icardi, Vecino complete dramatic late turnaround|
|Allegri, Chiellini defend Costa over spitting ban|
|Firmino only fit enough for bench duty|
|Kovac applauds Sanches ahead of Benfica homecoming|
|Tomlin confirms Steelers WR Brown was absent from facility on Monday|
|Mourinho tells United to follow Federer´s lead amid Young Boys pitch concerns|
|Costa banned for four Serie A matches for spitting|
|PGA Tour announces changes to FedEx Cup Playoffs format|
|Rashford to start against Young Boys, Mourinho confirms|
|Ryder Cup heading to Congressional in 2036|
|I never listen to stupid things - De Gea unconcerned by criticism|
|Aguero trains as Mendy sits out Man City session|
|Lampard fined after accepting improper conduct charge|
|Serie B suspended after Pro Vercelli win appeal|
|Mitchell returns to England as defence coach|
|Brady completes Cornet upset in Guangzhou|
|Lopetegui giving no guarantees to ´fighter´ Navas|
|Di Francesco denies racially abusing Costa|
|Saunders apologises for ´sickening´ online video|