Alex Iwobi scored twice as Nigeria fought back from 2-0 down against an Argentina side missing Lionel Messi to secure a stunning 4-2 friendly victory in Krasnodar.
Sergio Aguero scored his 36th international goal to move clear in third place on Argentina's all-time scoring list as Jorge Sampaoli's side looked set to prosper despite the absence of Messi, who had returned to Barcelona after featuring in the 1-0 win over Russia on Saturday.
Having drawn level with Hernan Crespo by scoring a late winner against the Russians, Aguero followed up his first international goal since June 2016 by tapping home Argentina's second to back up Ever Banega's free-kick opener.
Yet their comfortable cushion evaporated either side of the interval, with Kelechi Iheanacho inspiring a Nigeria fightback with a free-kick of his own in the closing stages of the first half.
Two goals in the space of three second-half minutes from Iwobi and Bryan Idowu swung the game further away from Argentina, with the former then slotting home a fourth to secure Nigeria just their second ever win over their South American opponents.
The astonishing turnaround came after Banega's 28th-minute free-kick gave Sampaoli's side a deserved lead - albeit they needed help from goalkeeper Daniel Akpeyi to break the deadlock.
After nudging the ball outside his own penalty area, a careless Akpeyi curiously allowed Aguero to quickly close the gap, forcing him to pick it up to prevent embarrassment.
He did not escape punishment for his error, however, as Banega curled the resulting set-piece opportunity into the net, Akpeyi opening up further space to target by taking an unnecessary step behind his wall.
Aguero added a second eight minutes later to move clear of Crespo, the striker tapping home Cristian Pavon's low cross from the right, and at that stage Argentina were coasting.
Nigeria had barely threatened in the first half but still managed to get back in the game, Iheanacho following Banega's example by scoring from a free-kick in the final minute of the first half.
FT: Argentina 2-4 Nigeria.— Super Eagles (@NGSuperEagles) November 14, 2017
We turned around a 2 goal deficit to beat Argentina.
The Krasnodar fans are giving our team a loud applause and standing ovation for an incredible performance#SoarSuperEagles.
The Leicester City striker's effort came after he had earlier left an impression on Nicolas Otamendi, catching his former Manchester City team-mate with an elbow.
Yet Iheanacho escaped with only a yellow card and, after halving the deficit, he heaped further pain on Argentina by setting up Nigeria's quick-fire double after the break.
Not content with a square pass from the right that allowed Iwobi to sweep home an equaliser, the 21-year-old forward played in the supporting Idowu to curl a right-footed effort beyond goalkeeper Agustin Marchesin.
Hit by a one-two combination, Argentina struggled to mount a response as they looked to get back on level terms in a game that had somehow escaped from their grasp.
With no Messi to inspire any late heroics, Iwobi wrapped up the victory for Nigeria, the Arsenal forward finishing with his left foot after swerving his way beyond Javier Mascherano.
|Orioles become first pro team to wear braille jerseys|
|Klopp hails ´brilliant´ Henderson|
|PSG attack lacked aggression, says Tuchel|
|Atletico Tucuman 0 Gremio 2: Libertadores holders draw first blood in QFs|
|Thomas plays down wrist worry|
|Rakitic wants more from Barcelona hat-trick hero Messi|
|My players aren´t s*** – Pochettino defends Spurs squad|
|Cubs reliever Morrow won´t return this season|
|Tebow expected to be back in Mets organisation next season|
|Inter can compete against anyone – Icardi revels in Champions League victory|
|Tuchel: PSG loss to Liverpool not logical or correct|
|Sturridge in best shape I´ve seen – Klopp|
|Milojevic celebrates ´fantastic´ occasion after Red Star´s 26-year wait|
|Rodrigo and Simeone salute Griezmann display|
|Seahawks DE Clark on Bears QB Trubisky: He´s nothing special|
|Carroll says Wilson has been ´over-trying a little bit´|
|Judge returns to Yankees´ starting lineup|
|Napoli boss Ancelotti takes aim at Red Star time wasting|
|Favre admits young Dortmund stars struggled in Bruges|
|Otavio would trade goal for Porto victory as he bemoans Schalke draw|
|Championship Review: Pacesetters Leeds crush Preston, Villa end five-game winless run|
|Neymar world-class but not a defender - Klopp says Liverpool targeted PSG star|
|Waiters injury update: Heat guard unlikely to be ready for start of season|
|Gojowczyk eliminates returning Tsonga in Metz|
|Liverpool enjoying best start in 57 years after PSG win|
|Galatasaray 3 Lokomotiv Moscow 0: Terim´s side make light work of Russians|
|Club Brugge 0 Borussia Dortmund 1: Super sub Pulisic scores late winner|
|Schalke 1 Porto 1: Fahrmann saves one penalty, but Otavio scores another|
|Red Star Belgrade 0 Napoli 0: Points shared as Italians fail to make possession pay|
|Liverpool 3 Paris Saint-Germain 2: Firmino strikes late as Reds edge five-goal thriller|
|Monaco 1 Atletico Madrid 2: Costa and Gimenez seal comfortable win|
|Chaos reigns in Serie B as league denies suspension claim|
|India secure Asia Cup victory despite valiant Hong Kong effort|
|Messi makes "extraordinary routine", says Valverde after Barca star surpasses Ronaldo|
|Spalletti´s Inter to take heart from Tottenham turnaround|
|Casillas features in landmark 20th Champions League campaign|
|Spurs deserved more from best performance of the season - Pochettino|
|Brown absent from Steelers facility on Monday due to ´personal matter´|
|Toronto´s Bussey given eight-match biting ban|
|Barcelona 4 PSV 0: Marvellous Messi lights up Camp Nou|
|Inter 2 Tottenham 1: Icardi, Vecino complete dramatic late turnaround|
|Allegri, Chiellini defend Costa over spitting ban|
|Firmino only fit enough for bench duty|
|Kovac applauds Sanches ahead of Benfica homecoming|
|Tomlin confirms Steelers WR Brown was absent from facility on Monday|
|Mourinho tells United to follow Federer´s lead amid Young Boys pitch concerns|
|Costa banned for four Serie A matches for spitting|
|PGA Tour announces changes to FedEx Cup Playoffs format|
|Rashford to start against Young Boys, Mourinho confirms|
|Ryder Cup heading to Congressional in 2036|
|I never listen to stupid things - De Gea unconcerned by criticism|
|Aguero trains as Mendy sits out Man City session|
|Lampard fined after accepting improper conduct charge|
|Serie B suspended after Pro Vercelli win appeal|
|Mitchell returns to England as defence coach|
|Brady completes Cornet upset in Guangzhou|
|Lopetegui giving no guarantees to ´fighter´ Navas|
|Di Francesco denies racially abusing Costa|
|Saunders apologises for ´sickening´ online video|
|Tianjin Quanjian 0 Kashima Antlers 3 (0-5 agg): Semi-final spot booked in resounding fashion|
|Madrid cannot live on Ronaldo´s glories, warns Ramos|
|Real Madrid are Champions League favourites, insists Man City coach Arteta|
|Stokes & Hales charged with bringing game into disrepute|
|Stephens slips to Vekic defeat in Tokyo|
|Simeone should teach Griezmann values - Ramos questions Ballon d´Or ambition|
|Arteta ready to step into Guardiola´s shoes after missing out on Arsenal job|
|Naive or scheming - Ozil´s agent slams Kroos, Neuer and Muller|
|Bolton´s Darby forced to retire after Motor Neurone Disease diagnosis|
|Root vows dressing support for Moeen over Ashes abuse claims|
|Madrid more dangerous without Ronaldo - Dani Alves|