For the second time in as many Wembley outings, Anthony Joshua faces a world-title showdown against a fellow former super-heavyweight Olympic gold medallist.
The 28-year-old Briton climbed off the canvas to dramatically halt Wladimir Klitschko in the penultimate round at England's national stadium in April last year.
On Saturday, he defends his IBF, WBA and WBO titles against Russia's Alexander Povetkin who, like Joshua and Klitschko, also reached the peak of the amateur boxing world before turning professional.
But starring in national colours on the biggest stage is no guarantee of glory in the paid ranks, as our rundown of the previous six big men to stand on the top step of the podium shows.
1996 – Wladimir Klitschko
Klitschko beat Tonga's Paea Wolfgramm in Atlanta to win Olympic gold, an opponent he would overcome as a pro four years later. By that stage, Klitschko had already lost to journeyman Ross Puritty and stoppage defeats to Corrie Sanders and Lamon Brewster seemingly left him with nowhere to go. But a remodelled style under the great Emanuel Steward helped the Ukrainian to 18 consecutive world title defences. Tyson Fury ended his run and he went out in a blaze of glorious defeat to Joshua.
Anthony Joshua is in camp for sparring. Two Super Heavyweight Olympic gold medalists in one ring that’s unique. pic.twitter.com/hLWYvLhGDj— Klitschko (@Klitschko) 19 August 2014
2000 – Audley Harrison
Superstardom beckoned for Harrison after his dominant triumph in Sydney but the outspoken Londoner rarely seemed suited to the professional ranks. His knockout of Michael Sprott to claim the European title while nursing a torn shoulder tendon marked a rare highlight, although it set up a somewhat pacifistic challenge for David Haye's WBA belt that made Harrison a subject of ridicule.
Nevertheless, he remains the trailblazer in terms of amateur boxing in the UK - his success in Sydney unlocking funding for those to come. Without 'A-Force', there would have been no Joshua, James DeGale or Amir Khan in the guise we know them today.
#onthisday in 2010 - I avenged my 2007 defeat to tough Michael Sprott with a KO victory in the 12th round for the European Title - having tore my RT chest/Pec muscle in the 3rd round, I used only my Left from then on, so this was a sweet sweet victory pic.twitter.com/8vy2DKmtMm— Audley Harrison MBE (@audleyharrison) April 9, 2018
2004 – Alexander Povetkin
A walkover at the expense of Egypt's Mohamed Aly granted Povetkin Olympic gold in underwhelming fashion, arguably a foreshadowing of a paid career that has combined impressive achievement with little fanfare. He outpointed Ruslan Chagaev to claim the WBA crown in 2011, defending his title four times before losing to Klitschko in Moscow. That remains Povetkin's only professional loss but eight subsequent wins have come alongside failed drugs tests and the associated reputational ruin. Wembley is his cavernous last chance saloon.
2008 – Roberto Cammarelle
A stalwart of the Olympic super-heavyweight scene, Cammarelle was never tempted to trade in his day job as an officer with the Italian State Police for a shot in boxing's glamour division. Beaten in the 2004 semi-final by Povetkin, Cammarelle stopped David Price in the semi-finals and overcame home favourite Zhang Zhilei in the same fashion for gold at Beijing 2008. Four years later, he came agonisingly close to defending his title…
2012 – Anthony Joshua
Locked at 18-18 with the technically superb southpaw Cammarelle, Joshua was awarded a countback victory to spark bedlam in London. AJ's march through his professional foes to date has been met with similarly rapturous acclaim. He made short work of Charles Martin to become IBF champion in April 2016, just his 16th contest since turning over. His defining night against Klitschko secured the WBA title and the Povetkin bout is his first while in possession of the WBO strap taken from Joseph Parker earlier this year.
2016 – Tony Yoka
British hopes of back-to-back super-heavyweight golds ended when Yoka was controversially awarded the verdict in his Rio final against Joe Joyce. The Frenchman has won all five of his professional fights, four inside the distance, but will not be adding to that record in his homeland any time soon. The French Anti-Doping Agency has handed him a one-year ban for missing several tests in the space of a year.
"There was negligence on my part, especially after the Olympics," Yoka said, as quoted by Boxing News. "But this is not a doping case. There has never been any medication taken. I'm told I could box abroad, but I'm not interested. I always said I wanted to box in my country and bring the first world heavyweight championship belt here."
Il y a deux ans le 21 aout 2016, je devenais Champion Olympique. Depuis tout a changé. Merci a tous pour le soutien, rien de tout ça ne serait possible sans vous pic.twitter.com/iGc9UH5rad— Tony YOKA (@TonyYoka) August 21, 2018
|Shaw: Man United showed too much respect to Juve|
|CAF Champions League Review: Al Ahly to face ES Tunis in final|
|76ers star Simmons dealing with back tightness|
|Roma boss Di Francesco hails ´extraordinary´ Dzeko|
|Pizzi and Jardel rue Benfica´s Ajax reverse|
|Championship Review: Leaders held at home, Smith suffers first Aston Villa defeat|
|Mourinho suggests Manchester United must spend to rejoin European elite|
|Manchester City reached their peak against Shakhtar - Guardiola|
|I really missed that winning feeling – Kroos|
|Lopetegui believes Real Madrid win can be turning point|
|Allegri: Juventus still making too many mistakes|
|Cole leads unbeaten Avellino to overtime victory|
|Mourinho hails ´amazing´ Chiellini and Bonucci after Juventus outclass United|
|Simeone glad to have Costa back for Dortmund clash|
|Lopetegui to remain in charge for El Clasico - Butragueno|
|Isner saves two match points to beat Norrie, Federer grinds out victory|
|Icardi happy at Inter ahead of Barca return|
|Marcelino satisfied with point after Valencia hold on at Young Boys|
|Hoffenheim 3 Lyon 3: Joelinton rescues a point after Kramaric´s double|
|Ajax 1 Benfica 0: Last-gasp Mazraoui seals dramatic win|
|Roma 3 CSKA Moscow 0: Dzeko turns on the style|
|Kovac lauds dominant Bayern|
|Shakhtar Donetsk 0 Manchester City 3: Silva sparkle to dominant display|
|Manchester United 0 Juventus 1: Dybala downs Mourinho´s men on Ronaldo´s return|
|Real Madrid 2 Viktoria Plzen 1: Benzema and Marcelo´s goals give holders first win in six|
|Lakers´ Rondo denies spitting on Rockets´ Paul|
|Robben and Rafinha want more from Bayern|
|Federer survives Krajinovic scare to maintain Basel run|
|Green accuses NBA of double standards, calls Lakers-Rockets suspensions ´garbage´|
|New York Giants send Apple to Saints|
|Morgan aims to solve Colombo mystery after record ODI defeat|
|AEK Athens 0 Bayern Munich 2: Lewandowski helps to further ease Kovac woes|
|Young Boys 1 Valencia 1: Hoarau penalty denies Marcelino´s men|
|Mourinho walks to Old Trafford as United arrive late again for Champions League|
|Bale and Benzema back for Madrid as Lopetegui rings changes|
|Carr denies ´fractured relationship´ with Raiders team-mates|
|De Bruyne to start for Manchester City against Shakhtar Donetsk|
|France lose Le Roux and Fofana for November Tests|
|Martino to leave Atlanta United amid Mexico links|
|Pochettino cautious over Eriksen return|
|Ancelotti an inspiration for PSG boss Tuchel|
|Persepolis 1 Al Sadd 1 (2-1 agg): Iranians into first AFC Champions League final|
|Wales boss Gatland returns to New Zealand after father´s death|
|Sri Lanka hand England their heaviest ODI defeat|
|Nuggets guard Will Barton undergoes surgery|
|Surprise package Svitolina closes in on semi-final berth|
|Alexander-Arnold targets glory at home and abroad|
|Pogba relishing emotional Juventus reunion|
|Alba hopes Lopetegui keeps Real Madrid job|
|Valverde not expecting Messi magical recovery|
|Wozniacki calms fears over knee injury|
|Maybe it´s my interviews - Klopp on Liverpool´s room for improvement|
|Language no barrier to Dortmund dangermen Reus and Alcacer|
|EPCR confirms no replay of Bath-Toulouse Champions Cup fixture|
|F1 Raceweek: Five the magic number as Hamilton eyes Mexico repeat|
|RFU to introduce in-season breaks for players|
|Nainggolan misses Barcelona trip|
|Wozniacki battles through knee complaint to down Kvitova|
|Alcacer: Two seasons at Barcelona not lost|
|Henderson, Keita to miss Liverpool´s Red Star clash|
|Khabib holds talks over Mayweather Moscow fight|
|Wolf in for Titz as Hamburg try to stop slump|
|Davies released from Wales squad as Evans comes in|
|Mbappe on track to match Messi and Ronaldo, says Giuly|
|Coleman, Kipchoge and Lyles among IAAF Male World Athlete of the Year shortlist|
|Serena Williams will win slams again sooner or later, says Seles|
|You always want the best – Ter Stegen open to Neymar return|
|Xavi: My teams will never use Mourinho´s style|
|I knew what I got myself into - LeBron appreciates Lakers are a work in progress|
|Mourinho: Ronaldo loves United but he will want to score|